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SCIENTIFIC NAME:
Vaccinium myrtillus
FAMILY NAME:
Ericaceae
COMMON NAME:
Bilberry
  Evidence for Efficacy (Human Data)
   Clinical Trials  (2)
   Observational Studies/Case Reports  (5)
   Traditional and Folk Use  (5)
 Safety Data
   Adverse Effects & Toxicity   (1)
   Interactions   (0)
   Contraindications   (0)
  Evidence of Activity
   Animal Studies  (18)
   Pharmacodynamics  (15)
   Analytical Chemistry  (43)
   Pharmacokinetics (ADME)  (7)
   Genetics & Molecular Biology  (13)
 Formulas/Blends
   Contemporary Formulas   (4)
   Folk Blends   (0)
   Patents   (1)
  Other Information
   Pictures & Distribution Maps  (7)
   Cultivation, Conservation & Ecology  (14)
   Related Links  (9)
 Dynamic Updates
   Live PubMed Searches   (15)
  History of Records
   History of Record (1)
 
 
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EVIDENCE FOR EFFICACY (HUMAN DATA)
 
Clinical Trials
  The hypothesis that V. myrtillus anthocyanosides improves normal night vision is not supported by evidence from rigorous clinical studies. Trials using subjects with impaired night vision warrant further investigation. Canter 2004
  [Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision--a systematic review of placebo-controlled trials.] Kramer 2004
Observational Studies/Case Reports
  According the scientific data, the mostly used plants for the prevention of complications of diabetes mellitus are: Ginkgo biloba, Allium sativum, Silybum marianum, Panax Ginseng, Carica papaya, Vaccinium myrtillus, Phaseolus vulgaris. [Article in Lithuanian] Savickiene 2002
  "Therapeutic value of Vaccinium myrtillus anthocyanosides in an internal medicine department " (no abstract) Amouretti 1972
  "The use of bilberry powder in dyspepsia in infants " (no abstract, Romanian) Tolan 1969
  "Effect of Vaccinium myrtillus anthocyanosides associated with betacarotenes on light sensitivity " (no abstract, Italian) Urso 1967
  "Study concerning the action of anthocyanoside extracts of Vaccinium Myrtillus on night vision " (no abstract, French) Jayle 1965
Traditional and Folk Use
  A review on vascular plants gathered for consumption in the Polish countryside shows that the wild edible plants which are still commonly gathered include two green vegetables and 15 folk species of fruits and seeds including Vaccinium myrtillus, V. oxycoccos. Luczaj 2007
  Discussion of the traditional consumption of wild edible plants in the rural communities of the Campoo (Cantabria), a region in northern Spain shows the most frequently cited species in the region (Rumex acetosa, Rosa canina, Vaccinium myrtillus, etc.) are widely consumed in the Mediterranean area. Pardo-de-Santayana 2005
  [Monograph. Vaccinium myrtillus (bilberry).] [No authors listed] 2001
  The role of oxidative stress in chronic fatigue syndrome (CFS) is an important area for the research and suggests the use of antioxidants in the management of CFS and specifically, the dietary supplements glutathione, bilberry, etc. may be beneficial. Logan 2001
         Dan Moerman's Native American Ethnobotany DB
SAFETY DATA
 
Adverse Effects & Toxicity
  Juice induced diarrhoea and carbohydrate malabsorption, studied in 15 healthy children with apple, grape & bilberry juices, not just due to fructose Hoekstra 1995
Interactions
No Records
 
Contraindications
No Records
 
EVIDENCE OF ACTIVITY
 
Animal Studies
  The chemoprotective activity of anthocyanin-rich extracts from bilberry, chokeberry and grape by assessing multiple biomarkers of colon cancer in male rats treated with a colon carcinogen, azoxymethane was investigated and its protective effect was confirmed. Lala 2006
  Long-term uptake of dietary supplements Mirtilene forte (extract from the fruits of Vaccinium myrtillus L.) or Adrusen zinco sharply decreased the level of protein oxidation in cytosol and mitochondrial extracts of hepatocytes of Wistar and of OXYS rats. Sinitsyna 2006
  The vascular changes associated with early diabetic retinopathy were investigated experimentally in streptozotocin-induced diabetic rats treated with antioxidants like troxerutin, Vaccinium myrtillus, and calcium dobesilate. Chung 2005
  The OXYS rat strain is the useful model for macular degeneration and senile cataract and long-term supplementation with bilberry extract is effective in prevention of macular degeneration and cataract. [Article in Russian] Fursova 2005
  Treatment with P-9801091 plant extract which includes Vaccinium myrtillus at a dose of 20 mg/kg body mass led to a significant increase in the catalytic concentration of glutathione S-transferases in the liver of diabetic NOD mice and a decrease in MDA concentration. Petlevski 2003
  Antidiabetis herbal preparation which includes Vaccinium myrtillus was examined on serum glucose and fructosamine in NOD mice in which ethanol extract from which ethanol was evaporated on a rotatory evaporator at a temperature of 45 degrees C, showed decrease in glucose and fructosamine. Petlevski 2001
  The in vivo study of skeletal muscle capillary permeability in diabetic rats on the effect of anthocyanosides of bilberry and ginkgo biloba was studied revealing that anthocyanosides prevented the increase in CFA and failure of lymphatic uptake of interstitial albumin. Cohen-Boulakia 2000
  Leaf extract orally to streptozotocin-diabetic rats for 4 days decreased plasma glucose by 26% and triglyceride by 39%. Single dose lowered in triglyceride in ethanol-treated normolipidaemic animals and in genetically hyperlipidaemic Yoshida rats Cignarella 1996
  Vaccinium myrtillus anthocyanosides @100mg/Kg for 2 or 4 wk improved ischemia damage such as decreasing leukocyte sticking to venule walls, preserved capillary perfusion; inhibited increased permeability of reperfusion and saved the arteriolar tone Bertuglia 1995
  Study of fruit aqueous extracts and tick-borne encephalitis virus in mice Fokina 1993
  V. myrtillus anthocyanosides injected to hamsters increased circulatory vasomotion frequency and amplitude Colantuoni 1991
  "Effect of Vaccinium myrtillus anthocyanins on triiodothyronine transport into brain in the rat " (no abstract) Saija 1990
  The anthocyanidin, 3,5,7-trihydroxy-2-(3,4-dihydroxyphenyl)-1-benzopyrylium, orally, countered gastric ulcers induced by stress, NSAID, ethanol, reserpine, histamine, cysteamine, acetic acid but not when pylorus ligated Magistretti 1988
  "Antiulcer and healing activity of Vaccinium myrtillus anthocyanosides " (no abstract) Cristoni 1987
  Anthocyanosides for 12 days limited the changes of vascular and blood-brain barrier permeability when hypertension was induced Detre 1986
  Bilberry anthocyanoside did not modify serum cholesterol levels in rabbits, but decreased the proliferation of the intima, extracellular matrix production, calcium and lipid deposition in the aorta, and DNA and lipid contents Kadar 1979
  Chloroform induced capillary permeability reduced by anthocyanosides i.p. (25--100 mg/kg) or oral (200--400 mg/kg) to rabbits. Protection is greater and more persistent than by rutin Lietti 1976
  "Phosphoglucomutase and glucose-6-phosphatase activities of the retina and anthocyanoside extracts from Vaccinium myrtillum " (no abstract, French) Cluzel 1969
Pharmacodynamics
  Anthocyanins and other phenolics from bilberry upregulate the oxidative stress defense enzymes heme-oxygenase (HO)-1 and glutathione S-transferase-pi in cultured human retinal pigment epithelial cells. Milbury 2007
  Anthocyanin-rich preparations of Vaccinium species (V. myrtillus, V. corymbosum, and V. oxycoccus) as well as a purified glycosylated anthocyanidin were compared for the protective activities of Vaccinium antioxidants with potential relevance to mitochondrial dysfunction and neurotoxicity. Yao 2007
  The potential coronary vasoactive and vasoprotective properties of three anthocyanin enhanced extracts prepared from chokeberry, bilberry, or elderberry was examined for the first time and their beneficial effect in vascular disease was observed. Bell 2006
  The effect of Mirtoselect, an anthocyanin mixture from bilberry, and cyanidin-3-glucoside was tested on intestinal adenoma formation in the Apc(Min) mouse model of intestinal carcinogenesis was studied. Cooke 2006
  Antimicrobial activity and mechanisms of phenolic extracts of 12 Nordic berries were studied against selected human pathogenic microbes. The most sensitive bacteria on berry phenolics were Helicobacter pylori and Bacillus cereus. Nohynek 2006
  Antioxidant activities of 15 purified bilberry anthocyanins together with pelargonidin 3-O-beta-D-glucopyranoside & 4'-O-methyl delphinidin 3-O-beta-D-glucopyranoside (MDp 3-glc), were evaluated to study structure-antioxidant activity relationship & any synergism among them. Rahman 2006
  A blueberry extract and two anthocyanin-derived extracts were prepared and their abilities to inhibit lipid peroxidation, induced by 2,2'-azobis(2-methyl-propanimidamide) dihydrochloride in a liposomal membrane system were examined. Faria 2005
  Extracts of raspberry, strawberry, cranberry, elderberry, blueberry, bilberry, and OptiBerry, a blend of the 6 berries, with & without clarithromycin were evaluated on Helicobacter pylori which showed that all berry extracts inhibited H. pylori, & also increased its to clarithromycin. Chatterjee 2004
  The antioxidant protection toward lipid oxidation was best provided by lingonberry and bilberry phenolics followed by black currant and raspberry phenolics. Bilberry and raspberry phenolics exhibited the best overall antioxidant activity toward protein oxidation. Viljanen 2004
  Commercially prepared grape (Vitis vinifera), bilberry (Vaccinium myrtillus L.), and chokeberry (Aronia meloncarpa E.) anthocyanin-rich extracts (AREs) were investigated for their potential chemopreventive activity against colon cancer which revealed varying degrees of growth inhibition. Zhao 2004
  The bilberry extract and the anthocyanins, bearing delphinidin or malvidin as the aglycon, were effective in inhibiting the growth of HL60 human leukemia cells and HCT116 human colon carcinoma cells in vitro and the inhibition of the growth of HL60 cells was through induction of apoptosis. Katsube 2003
  Trace amounts of V myrtillus extract (15 - 20 micrograms/mL) reduces oxidation of human low density lipoproteins Laplaud 1997
  Quinone reductase is doubled by fruit ethyl acetate extract of bilberry, bluberry, cranberry & lingonberry by 1.0, 4.2, 3.7 & 1.3 mcg tannin equiv. Ornithine decarboxylase is inhibited by proanthocyanidin fractions while anthocyanidin is inactive Bomser 1996
  Platelet activating factor inhibited by 19 out of 59 plant extracts, esp. by Geum, Solanum, Symphytum & Vaccinium vitis-idaea Tunon 1995
  Bilberry aqueous extract inactivated tick-borne encephalitis Fokina 1991
Analytical Chemistry
  A rapid, reliable, and reproducible solid-phase extraction, high-performance liquid chromatography (HPLC), and mass spectrometry techniques are described for the isolation, separation, and identification of bilberry anthocyanins in human plasma and urine. Cooke 2006
  The composition of cutin monomers from 5 Finnish berries, including lingonberry and bilberry was determined by GC-(EI)MS analysis either as methyl esters or as TMSi esters, with OH groups derivatized to TMSi ethers. Kallio 2006
  Detection of deliberate adulteration such as amaranth in commercial samples of Vaccinium myrtillus or bilberry fruit, indicates need for more sophisticated, methods of analysis such as HPLC with photodiode array detection as a minimum. Penman 2006
  Antioxidant properties of medicinal plants, including V. myrtillus, may be used for prophylaxis and medical treatment of free radical pathologic conditions. [Article in Russian] Ryzhikov 2006
  13C CPMAS NMR spectra of dietary fiber powders from aronia (chokeberry), bilberry, black currant and apple were recorded. The fiber powders obtained from berries contain significant amounts of anthocyanins, as indicated by their dark violet color, but not verified by chemical shifts. Wawer 2006
  The content and profile of the phenolic compounds present in six different berries including bilberry, cowberry, cranberry & strawberry in Northern Europe was evaluated by capillary electrophoresis and their antioxidant activity was determined. Ehala 2005
  High-speed counter-current chromatography was used for the separation of anthocyanins on a preparative scale from bilberry fruit crude extract (Vaccinium myrtillus, Ericaceae) with a biphasic solvent system. Du 2004
  The reactivities of twelve major anthocyanins identified in bilberry extracts towards nitric oxide and peroxynitrite were studied in vitro using capillary zone electrophoresis. Ichiyanagi 2004
  An HPLC method using isocratic elution was established for the analysis of fifteen anthocyanins contained in bilberry (Vaccinium myrtillus L.). The detection limit was 0.3 pmol for delphinidin 3-O-beta-D-glucopyranoside. Ichiyanagi 2004
  Capillary zone electrophoresis (CZE) mobilities of fifteen anthocyanins in bilberry extract were completely characterized. Ichiyanagi 2004
  Anthocyanin extracts of two blueberries, Vaccinium myrtillus (bilberry) and Vaccinium ashei (rabbiteye blueberry), and of three other berries, were analyzed by high-performance liquid chromatography coupled with photodiode array detection and electrospray ionization - mass spectrometry. Nakajima 2004
  A study was conducted to determine the presence of resveratrol, pterostilbene, and piceatannol in 10 Vaccinium berries including Vaccinium myrtillus (bilberry), using gas chromatography/mass spectrometry. Rimando 2004
  Anthocyanin contents and GST activities of bilberry (Vaccinium myrtillus L.) were investigated in two experiments conducted in June (Exp. I: active growth) and in August/September (Exp. II: beginning of frost hardening) in Northern Finland. Taulavuori 2004
  An HPLC method and an acid hydrolysis HPLC method for the analysis of anthocyanins and anthocyanidins in bilberry extracts was developed. Zhang 2004
  S-100 proteins in plants of following species: plantain (Plantago major L.), aloe (Aloe arborescens L.), and bilberry (Vaccinum myrtillus L.) have been identified. [Article in Russian] Krasnov 2003
  Resveratrol in the fruits of bilberry, the lowbush "wild" blueberry, the rabbiteye blueberry and the highbush blueberry were measured using a new assay based on high-performance liquid chromatography-tandem mass spectrometry. Lyons 2003
  The content and distribution of UV-absorbing phenolic compounds was investigated in leaves of three species of Vaccinium such as V. myrtillus, V. vitis-idaea and V. uliginosum, co-existing at a site in north Sweden. Semerdjieva 2003
  A fast reversed-phase HPLC method for quantification of the hydrophilic carboxylic acids was developed and used for analyses of cranberry, lingonberry, and blueberry juices. The level of hydrophilic carboxylic acids in blueberries was 0.35-0.75%. Jensen 2002
  A narrow-bore HPLC/ESI-MS method was used to investigate anthocyanin contents of black bilberry (Vaccinium myrtillus L.), blackberry and mulberry. Dugo 2001
  Delphinidin, cyanidin, petunidin, pelargonidin, peonidin, and malvidin contents of bilberry (Vaccinium myrtillus), black currant, strawberry and Vitis vinifera red wine were determined by a high-performance liquid chromatographic method. Nyman 2001
  An alpha4-fucosyltransferase (alpha4-FucT) from Vaccinium myrtillus, which catalysed the biosynthesis of the Lewis(a) adhesion determinant was partially characterized. Palma 2001
  Extracts of selected medicinal plants including anthocyanins (Vaccinium myrtillus), isoflavones (Glycine max, soybean), were examined by electrospray mass spectrometry. Mauri 2000
  Nutrients & pectin in red bilberry Zaitsev 1997
  14 batches of dried leaves contain: total polyphenols 13%, tannins 7.8%, total flavonoids 2.9%, 1.4%, quercetin 3-glucuronide 1 %, hyperoside 0.2%, chlorogenic acid 3%. Highest in young leaves Fraisse 1996
  RP-HPLC is a good method for standardization of bilberry extracts by the separation and quantitative estimation of 12 anthocyanins Petri 1994
  Anthocyanin and polyphenol content and radical scavenging Costantino 1992
  Root of V. scopulorum contains beta-amyrin, 3-epi-ursolic acid, methyl maslinate, 3 beta-acetoxy-delta 7-cholest-7-ene, protocatechuic acid, ethyl n-hexacosanoate and ethyl n-tetracosanoate Shang 1992
  "Phenolic acids in leaves of Arctostaphylos uva ursi L., Vaccinium vitis idaea L. and Vaccinium myrtillus L " (no abstract) Dombrowicz 1991
  "Anthocyanosides extracted from Vitis vinifera, Vaccinium myrtillus and Pinus maritimus. I. Elastase-inhibiting activities in vitro. II. Compared angioprotective activities in vivo " (no abstract) Jonadet 1983
  The bark and tips of conifer twigs, twigs of oak and mountain ash, bilberry and heather plants, i. e. perennial plants, are particularly high in cadmium Anke 1979
  Bilberry plants is one of the highest in manganese content at 2,080 mg/kg, compared with spruce twigs 984, oak twigs 791, heather 754 mg/kg Anke 1979
  "High-performance liquid chromatographic separation and quantitative determination of arbutin, methylarbutin, hydroquinone and hydroquinone-monomethylether in Arctostaphylos, Bergenia, Calluna and Vaccinium species " (no abstract) Sticher 1979
  "Contents of manganese and vitamin C in the fruits of bilberriers and red berries (Vaccinium myrtillus L.) and red berries (Vaccinium vitis-idaea L.) growing in highly industrialized areas " (no abstract, Polish) Lorek 1978
  Anthocyanosides of V. myrtillis reduce collagenase induced permeability of the blood brain barrier and accelerate the recovery of normal permeability Robert 1977
  "Phytochemical investigation of leaves and fruits of Vaccinium myrtillus " (no abstract) Friedrich 1973
  "Tannin-producing substances in the leaves and fruits of the bilberry " (no abstract) Friedrich 1973
  "Chemotaxonomy of Ericaceae: isolation and identification of triterpenes and steroids from Vaccinium uliginosum " (no abstract, German) Nees 1973
  "Studies on the constituents of Vaccinium bracteatum Thunb. II. On the constituents of the flowers, particularly on the structure of vaccinoside, a new iridoid glycoside " (no abstract) Sakakibara 1973
  "Determination of tannin in leaves of bilberry " (no abstract) Schonert 1970
  "On the isolation of 4-hydroxyphenyl-beta-gentiobioside from Vaccinium vitis-idaea L " (no abstract, German) Thieme 1969
  "Isolation of bilberry anthocyanines and their pharmacologic activity. Preliminary study " (no abstract, Italian) Cantarelli 1968
  "The anthocyans of Beta vulgaris var. rubra (red beets), Vaccinium myrtillis (whortleberries), Vinum rubrum (red wine) and their significance as cell respiratory activators for cancer prophylaxis and cancer therapy " (no abstract, German) Seeger 1967
  "On the occurrence of salidroside in the leaves of the red whortleberry (Vaccinium vitis-idaea L.) " (no abstract) Thieme 1966
Pharmacokinetics (ADME)
  It is shown that plasma quercetin increase up to 50% in subjects consuming 100 g/day of bilberries, black currants, and lingonberries as a part of their normal diets for 2 months. Erlund 2006
  Investigation of urine and plasma samples were collected from 32 rats receiving control diet or chokeberry-, bilberry-, and grape-enriched diet for 14 wk suggests the bioavailability of the anthocyanin derivatives that are commonly found in commercially available colorants. He 2006
  To clarify how structural diversity of anthocyanins relates to their in vivo function, bioavailability was precisely studied in rats using bilberry (Vaccinium myrtillus L.) extract (Bilberon 25) as an anthocyanin source that contains 15 different anthocyanins. Ichiyanagi 2006
  Investigation of anthocyanin absorption including bilberry anthocyanins (45.2 nmol/min) after in situ perfusion of the jejunum + ileum in rats demonstrated that anthocyanin glycosides are rapidly and efficiently absorbed from the small intestine. Talavera 2004
  Serum quercetin concentrations were significantly higher in the 20 subjects consuming 100 g/day of berries which contains black currants, lingonberries and bilberries for 8 weeks compared to the control group (20 subjects). Erlund 2003
  Single oral dose of V. myrtillus anthocyanosides to rats reach peak (2-3 micrograms/ml) level after 15 min and then rapidly declines within 2 h. Only 5% is assimilated and elimination occurs mostly through urine and bile Morazzoni 1991
  Vaccinium myrtillus anthocyanins partition more to the kidneys and skin than plasma, explaining long-lasting activity on capillaries Lietti 1976
Genetics & Molecular Biology
  The genetic structure of the root endophytes Phialocephala fortinii s.l. and Acephala applanata was analyzed in two undisturbed forests. A total of 606 strains isolated from surface-sterilized, fine roots of Picea abies and Vaccinium myrtillus were examined. Grunig 2006
  It is demonstrated that extracts from bilberries, and the flavonoid quercetin, abundant in bilberries, induce the fra-1 promoter and the cellular content of Fra-1 mRNA. Myhrstad 2006
  Rhizosphere microbial communities associated with Vaccinium myrtillus collected from the native pine forest were investigated by using multiplex terminal restriction fragment length polymorphism fingerprinting method. Singh 2006
  The expression of flavonoid biosynthesis genes during the development of bilberry (Vaccinium myrtillus) fruit in relation to the accumulation of anthocyanins, proanthocyanidins, and flavonols in wild berries and in color mutants of bilberry have been studied. Jaakola 2002
  A simple and efficient method is described for isolating high quality RNA from bilberry fruit and yields high-quality RNA suitable for cDNA based methodologies. Jaakola 2001
  Human Lewis(a) type determinant in glycoproteins secreted by a plant cell suspension culture of Vaccinium myrtillus Melo 1997
  There were no significant correlation between soil 137Cs concentration and levels in plants (Vaccinium, Juncus, Calluna, Picea) McGee 1996
  "Magnetic circular dichroism studies on Vaccinium myrtillus cationic peroxidases " (no abstract) Melo 1995
  Vaccinium mirtyllus peroxidase (which can oxidize guaiacol) has 500 hour half life in isooctane reversed micelles Setti 1995
  Ixodes ticks are in greater density in Vaccinium and Bracken areas than heather areas Sheaves 1995
  Three major polypeptides of 65, 60, and 14 kD in floral buds increased in response to chilling and decreased to the prechilling level with the initiation of budbreak Muthalif 1994
  V. myrtillus fruit is an important part of wild ptarmigan diet Moss 1975
  "Enzymatic activities of retina and anthocyanoside extracts of Vaccinium myrtillus " (no abstract, French) Cluzel 1970
FORMULAS/BLENDS
 
Contemporary Formulas
  To characterise the most complex xyloglucan structures in bilberries, xyloglucans were enzymatically degraded and the oligosaccharides obtained were analysed. More than 20 different building blocks were found to make up the xyloglucan polymer. Hilz 2007
  Two cationic peroxidases isolated from Vaccinium myrtillus were encapsulated in reverse micelles of bis(2-ethylhexyl)sodium sulfosuccinate / isooctane. By using a central composite design, some relevant parameters for the enzymatic activity, were analyzed. Morna-Gomes 1999
  Standardization of the anthocyanoside complex of Vaccinium myrtillus Bonati 1991
  Radiation preservation of bilberry and other fruits Thomas 1986
Folk Blends
No Records
 
Patents
         Conduct a search on V. myrtillus or bilberry in the title, abstract or claims section (excl. horticultural varieties) of the US patent database
OTHER INFORMATION
 
Pictures & Distribution Maps
         henriettesherbal.com
         markinfo
         naturephoto
         pbase.com
         Image of Bilberry at TAMU-BWG
         Image of Bilberry at TAMU-BWG
         Distribution map in Western United States
Cultivation, Conservation & Ecology
  Investigation of separate effects of ammonium & nitrate on boreal forest understorey vegetation shows the dwarf-shrubs dominating the plant community, Vaccinium myrtillus & V. vitis-idaea, took up little of added N independent of chemical form, and their growth did not respond to N treatments. Nordin 2006
  Correlations between mast fruiting of bilberry Vaccinium myrtillus and peak levels of Clethrionomys-voles have been reported from both Norway and Finland. Selas 2006
  Rising atmospheric CO(2) likely affects leaf chemistry in two important dwarf shrub species (Vaccinium myrtillus and V. uliginosum) at the alpine treeline, leading to changes in feeding behavior, growth, and reproduction of the most important insect herbivore in this system. Asshoff 2005
  The morphology of flowers, flowering dynamics and composition of insect visiting flowers of Ericaceae species including Vaccinium myrtillus, V. uliginosum, and V. vitis-idaea L. were studied. [Article in Russian] Dlusskii 2005
  Exclusion of insectivorous birds increased the frequency of larval damage on Vaccinium myrtillus shoots, indicating higher larval densities. This effect was stronger in fertilized than in unfertilized plots, indicating higher bird predation in fertilized plots. Strengbom 2005
  Nitrogen (N)-induced changes in the constitutive levels of soluble conjugated amines do not seem to explain the increased parasite susceptibility of V. myrtillus under N enrichment. Witzell 2005
  Results of experiments on Vaccinium myrtillus L. leaves support evidence of the protective role of flavonoids and hydroxy cinnamic acids against high solar radiation in plants. The roles of different flavonoid compounds as a defense against stress caused by sun exposure is discussed. Jaakola 2004
  The effects of nitrogen (N) fertilization on the phenolic status of Vaccinium myrtillus leaves were studied to assess whether N amendment affects potentially defensive phenolic metabolites such that it could have consequences for the interaction with a parasitic fungus. Witzell 2004
  Short- as well as long-term plant nitrogen uptake by Deschampsia flexuosa, Picea abies and Vaccinium myrtillus from 15NO3-, 15NH4+ and (U-13C, 15N) arginine, glycine or peptides was investigated. Persson 2003
  Possible links between the occurrence of Vaccinium myrtillus, V. vitis-idaea and Deschampsia flexuosa and rates of nitrogen deposition were investigated in 557 coniferous forest stands. Strengbom 2003
  Nitrate reductase activity was studied in the foliage of five subarctic species including the Ericaceous shrub bilberry (Vaccinium myrtillus L.), naturally growing in a forest. Krywult 2002
  The influence of extreme pollution on the inorganic chemical composition of some 9 different plants species including Vaccinium myrtillus was described. Reimann 2001
  Uptake of Al, Cu, Fe, Mn, Ni, Ca, K, Mg, P, and S in Empetrum nigrum L. ssp. hermaphroditum Hagerup and Vaccinium myrtillus L. from Ni, Cu and SO2 contaminated sites in Sor-Varanger, northern Norway, were investigated. Uhlig 2001
  Study on the effect of climatic warming on the dehardening potential of bilberry (Vaccinium myrtillus L.) in a northern boreal environment suggest that a small elevation in air temperature can accelerate dehardening in the bilberry. Taulavuori 1997
Related Links
         allwebhunt.com
         Bilberry at CalFlora
         DiaMedBase
         fitoterapia.in
         Taxon information at GRIN
         Bilberry at HortiPlex
         Monograph at NCCAM Herbs-at-a-Glance
         plantquarantineindia.org
         Bilberry at Plants for the Future
DYNAMIC UPDATES
 
Live PubMed Searches
  Vaccinium myrtillus and Analytical Chemistry
  Vaccinium myrtillus and Animal Studies
  Vaccinium myrtillus and Case Reports
  Vaccinium myrtillus and Clinical Trials
  Vaccinium myrtillus and Drug Interactions
  Vaccinium myrtillus and Ethnobotanical Use
  Vaccinium myrtillus and Genetics
  Vaccinium myrtillus and In Vitro Studies
  Vaccinium myrtillus and Pharmacodynamics
  Vaccinium myrtillus and Pharmacokinetics
  Vaccinium myrtillus and Preparations & Formulary
  Vaccinium myrtillus and Reference Standards
  Vaccinium myrtillus and Safety & Toxicology
  Vaccinium myrtillus and Therapeutic Activity
  Vaccinium myrtillus and Tissue Culture

HISTORY OF RECORD
RESEARCHED BY: Soaring Bear, Ph. D.     1998
RESEARCH UPDATED BY: Michael C. Tims, Ph. D. cand.    2001
REVISED BY: J Mohanasundaram, MD, PhD    May 2007
 
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